“Myriad was able to isolate the BRCA genes in the first place largely because it had access to government-financed public databases.”
“A more important consequence than random coin tosses is the uncertainty that is the basis of the random DNA mutations necessary for evolution. A truly indeterminate local physics guarantees that this process has some “noise,” and that mutation is always possible in principle. The chemistry of DNA replication involves, after all, exchanges of electrons and atoms, which are quantum objects.”
“The U.S. government’s investment of $14.5 billion in human genome science has helped to spur nearly $1 trillion in economic activity and create tens of thousands of jobs over the past 24 years, according to a new study.”
Genome Science Said to Have Economic Payoff [WSJ]
Despite all of the noise around the human genome, here’s an interesting tidbit,
In 1990, for example, only 61 diseases or health conditions had an identified cause linked to genes; today, there about 4,850, according to United for Medical Research, an advocacy group, which funded the latest study.
And the number is expected to increase as statistical methods are improved upon and more genome sequences become available.
Tumblr’s Mad Geneticist wrote a bit about the differences between genotyping (think 23&Me, ancestry stuff) and sequencing (the raw, good stuff).
“I join the judgment of the Court, and all of its opinion except Part I–A and some portions of the rest of the opinion going into fine details of molecular biology. I am unable to affirm those details on my own knowledge or even my own belief. It suffices for me to affirm, having studied the opinions below and the expert briefs presented here, that the portion of DNA isolated from its natural state sought to be patented is identical to that portion of the DNA in its natural state; and that complementary DNA (cDNA) is a synthetic creation not normally present in nature.”